In L2-IL1β mice, p53 mutation increased progenitors expansion and lineage-tracing with a shift from metaplasia to dysplasia. scRNA-seq revealed dysplastic cells arise directly from mutant progenitors ...

BACKGROUND Biopsy specimens obtained from the gastro-oesophageal junction can reveal intestinal metaplasia in patients presenting for routine upper endoscopy. The site of biopsy may play a critical ...

Your esophagus pathology report: Barrett's esophagus and dysplasia. Jencks DS, Adam JD, Borum ML, Koh JM, Stephen S, Doman DB. Overview of current concepts in gastric intestinal metaplasia and ...

Intestinal metaplasia (IM) occurs when the body replaces ... These abnormal cells in the stomach are referred to as gastric dysplasia. This may eventually develop into gastric adenocarcinoma ...

Esophageal adenocarcinoma arising from Barrett's metaplasia has regional variations in the west. Gastroenterology 122(2), 588-590 (2002). Haggitt RC. Barrett's esophagus, dysplasia and adenocarcinoma.

Of the 77% majority of patients with simple metaplasia on their index endoscopy ... esophageal adenocarcinoma had either ulcerations or dysplasia at index endoscopy. These findings enhance ...

Additionally, erosions and cysts may be found in non-neoplastic mucosa. In most prophylactic gastrectomies reported so far, intestinal metaplasia and H pylori infection are absent (families from North ...

Cancer is the second greatest cause of mortality worldwide. According to estimates from the World Health Organization, there were approximately 19 million new cancer cases globally in 2020, resulting ...

Objective: To evaluate the role of chromohysteroscopy in improving diagnostic accuracy of endometrial biopsy in cases of AUB. Design: Cross sectional interventional study. Materials and Methods: This ...