Initially 12g/m 2 IV infusion over 4 hours; may be increased to 15g/m 2; see literature for leucovorin rescue dosing with high-dose methotrexate. Be fully familiar with this drug's toxicity before ...

The second recommendation deals with the initial and maximum doses of methotrexate, time intervals between dose adjustments, and changing from oral to parenteral administration if needed.

Adverse drug reactions are more common in the liver than in the kidneys for patients with rheumatoid arthritis using ...

Patients with RA who achieve LDA with certolizumab plus methotrexate had similar rates of worsening symptoms following either ...

R2 was a factorial randomization resulting in four arms: high-dose methotrexate (HDM) with pulses, HDM without pulses, standard interim maintenance (SIM) with pulses (standard of care), and SIM ...

Is methotrexate covered by Medicare? It may be. You can call your Medicare plan provider to learn whether your particular plan covers the cost of the drug. There are many types of Medicare plans ...

Initially 12g/m 2 IV infusion over 4 hours; may be increased to 15g/m 2; see literature for leucovorin rescue dosing with high-dose methotrexate. Be fully familiar with this drug's toxicity before ...