Microglia, the brain's immune cells, usually serve as diligent guardians. They eliminate intruders such as microbes and clear ...

Glia are essential for brain functioning during development and in the adult brain. Here, we discuss the various roles of both microglia and astrocytes, and their interactions during brain development ...

Now, two independent studies have honed in on inflammatory microglia as a potential therapeutic strategy. In mice, induction of T regulatory (T reg) cells or supplementation with a metabolic ...

Common treatments may not be as effective for women as they are for men, mouse model reveals In a nutshell Research reveals ...

The injection of IgG from patients with NMOSD in the vitreous cavity of mice led to the upregulation of complement C3 expression in the retinal Müller cells and the activation of the microglia. The ...

Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...

Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory ...

Notably, microglia spatially associated with amyloid plaques exhibited increased expression of TREM2 and ApoE compared to ...

A comprehensive Thought Leaders Invited Review in Brain Medicine highlights the crucial role of CD2-associated protein (CD2AP ...

In particular, the researchers observed a significant increase in the number and turnover of microglia, the primary immune cells found in the central nervous system. The study also revealed neuronal ...