Mitochondrial fusion is the physical merging of the outer and then the inner mitochondrial membranes of two originally distinct mitochondria. Mitochondrial division is the breaking apart of one ...

Researchers at Johns Hopkins Medicine discovered that mitochondrial proteins Parkin, PINK1, and OMA1 act as guardians of ...

In the first panel, two separate mitochondria are labeled green and red (indicated by arrows). Ten seconds later (see second panel), these two mitochondria have fused into one, as shown by the ...

Calcium transport into and out of mitochondria is central to cellular energy production and cell death. To maintain the ...

Scientists created a stem cell-based method to produce high-quality mitochondria at scale, enabling effective treatments for ...

Mitochondria are commonly found as extended reticular webs whose overall morphology depends on frequent fission and fusion of mitochondrial tubules. These processes require distinct GTP-binding ...

A Parkinsonian mystery—how PINK1 locks onto malfunctioning mitochondria—now has a structural solution. Researchers at the University of Melbourne led by Sylvie Callegari, Alisa Glukhova, and David ...

The protein detects when energy-producing structures called mitochondria become damaged, and will gather on their surface. PINK1 then signals for other proteins to help remove the broken component ...

View Full Profile. Learn about our Editorial Policies. B.H. Abuaita et al., “Mitochondria-derived vesicles deliver antimicrobial reactive oxygen species to control phagosome-localized Staphylococcus ...