The study was published under the title "Metabolic rewiring caused by mitochondrial dysfunction promotes mTORC1-dependent skeletal aging" in Science Advances. The researchers undertook a specific ...

It is this critical window that Dr. George Porter and his research team are trying to better understand. A pediatric cardiologist and researcher, Porter is leading efforts to uncover how mitochondria ...

You will be redirected to our submission process. Mitochondrial homeostasis is crucial for the maintenance of cellular equilibrium. In neurons, which are non-regenerative cells, mitochondrial ...

Mitochondria are cytoplasmic organelles found in most eukaryotic cells. They are formed from an outer membrane, a highly invaginated inner membrane containing cristae, and a matrix. Mitochondria ...

Mitochondria in intact cells can transiently accumulate calcium during cell stimulation. The heterogeneity of the response, the extremely high calcium concentrations reached in the mitochondrial ...

And, for one type of organelle, that principle is now being tested in practice. Mitochondria, the organelles in question, are best known as power packs—places where glucose molecules are ...

Scientists have developed a stem cell-based method to mass-produce high-quality mitochondria, achieving an 854-fold increase in output and greatly enhancing therapeutic potential for diseases like ...

Researchers have identified a molecule that helps more mitochondria function properly. A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic ...

TMEM65 aids in calcium removal from mitochondria, preventing harmful calcium overload linked to heart failure and Alzheimer's disease. This discovery could lead to new therapeutic strategies ...

Damage to the genetic material of mitochondria—the mitochondrial DNA or mtDNA for short—can lead to diseases such as Parkinson's, Alzheimer's, amyotrophic lateral sclerosis (ALS ...