The mitochondria act as the energy factories of our cells, creating ATP that drives our bodily functions. Inefficiencies in mitochondrial function have been associated with a variety of health ...

When mitochondria fail, the consequences can be devastating – particularly for children with genetic disorders that rob cells of their ability to produce energy. Now, researchers at the University of ...

Researchers have identified a molecule that helps more mitochondria function properly. A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic ...

The cell relies on mitochondria to function as its power generator through ATP (adenosine triphosphate) production that supports all biochemical reactions in the body. With age comes the natural ...

Enhancing the activity of the retromer complex, particularly the protein VPS35, improves mitochondrial function, offering potential therapeutic strategies for mitochondrial and age-related diseases.

Researchers at the University of Gothenburg have identified a molecule that helps more mitochondria function properly. Mitochondrial diseases caused by POLG mutations vary in severity. In young ...

In Parkinson’s disease (PD), damaged mitochondria build up in the dopaminergic system of the substantia nigra, partly due to impaired mitochondrial autophagy (mitophagy) and autophagosome accumulation ...

This review summarizes the cell death patterns and molecular mechanisms associated with heart disease and mitochondrial dysfunction. The heart is an organ that has an essential role in human body, ...

State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China ...

the distinct function of RAB11B is less clear. Methods and Results: Our proteomic analysis of RAB11A or RAB11B interactome suggested a potential RAB11B specific involvement in regulating mitochondrial ...