In isolated stem cells and mice with Dnmt3a mutations, the team tested the effect of MitoQ and d-TPP—molecules, which disrupt the normal function of mitochondria and prevent them from producing ...

After 50 years of mystery, researchers at the University of Cambridge have revealed how a molecular machine inside mitochondria enables cells to generate energy from sugars, a process crucial to all ...

But which part of the mitochondria’s structure or function protected the cells remains unknown, says Hayakawa. Lung cells might also benefit from a mitochondrial boost during a crisis ...

Researchers have identified a molecule that helps more mitochondria function properly. A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic ...

And, shortly afterwards, the perfused mitochondria took up residence in the damaged heart muscle, restoring its function in the longer term. Dr McCully now hopes to extend this approach ...

While mitochondrial transplantation has emerged as a promising avenue for restoring tissue function, its clinical potential has been severely hampered by the scarcity of viable mitochondria.

Damage to the genetic material of mitochondria—the mitochondrial DNA ... are eliminated much more quickly and that mitochondrial function improves significantly when the activity of the retromer ...

The cell relies on mitochondria to function as its power generator through ATP (adenosine triphosphate) production that supports all biochemical reactions in the body. With age comes the natural ...

Now, on page 57 of this issue, an elegant paper by Montero and colleagues 1 reveals further complexity in one of the most studied, yet most controversial, functions of mitochondria — their ...

Genome-wide association studies have identified nearly 800 genetic loci associated with kidney function, yet more than 90% of these variants are located in noncoding regions. Specific genes and ...

Researchers at the University of Gothenburg have identified a molecule that helps more mitochondria function properly. Mitochondrial diseases caused by POLG mutations vary in severity. In young ...

What we do is woven into every UBS capability. From Technology and Compliance to Human Resources and Treasury. Most of our support and control functions are fully shared among the business divisions, ...