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The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...
AMX0114 is an antisense oligonucleotide made to prevent or slow the degeneration of axons, which is a key driver of ALS ...
Human induced pluripotent stem cell-derived motor neuron axons fan out and embed themselves into the human muscle tissue, which creates a large connection surface. Disclaimer: AAAS and EurekAlert!
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