The ECM components in fibrotic liver are similar regardless of the underlying cause. Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells ...

Université Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d’Imagerie Biomédicale Multimodale (BioMaps), Service Hospitalier Frédéric Joliot, 4 place du général Leclerc, Orsay 91401, France Department of ...

With regard to activated PSC, it is currently not clear whether these are different from myofibroblasts of the pancreas and whether there are markers to differentiate these two cell types. However, ...

Fibroblast growth factors (FGFs) signal through FGF receptor tyrosine kinases to regulate a wide range of biological processes during development and adulthood. FGF receptors (FGFRs) are involved ...

The Prenatal Screening Program. Maternal Serum Markers of Fetal Abnormalities: Progress in Prenatal Screening. MedGenMed 1(1), 1999. [formerly published in Medscape Women's Health eJournal 1(4 ...

However, recent advances in single-cell RNA sequencing technology have revealed that resident macrophages throughout the gut are functionally specialised to carry out specific roles in the niche they ...