The complexity of human metastatic cancer is difficult to mimic in mouse models. As a consequence, seemingly successful studies in murine models do not translate into success in late phases of ...

significantly inhibits tumor growth in murine tumor models and is well-tolerated. mPH-762-mediated silencing of PH-762 within the TME may generate memory-specific T cells, promoting IFN-γ release ...

A major breakthrough in the fight against cancer has just been achieved. An innovative method, successfully tested in the ...

Scientists at the University of Wisconsin Madison and Dana-Farber Cancer Institute recently presented preclinical data for the radiopharmaceutical therapy candidate [177Lu]PNT-6555.

However, despite it being effective, many patients experience recurrences, and others become unresponsive. The activation of the intracellular transmembrane receptor stimulator of interferon genes ...

In preclinical trials on a murine model of breast cancer, the hydrogel showcased remarkable efficacy. A single injection of the hydrogel, loaded with the chemotherapy drug Doxorubicin, resulted in ...