Karuna filed KarXT for approval in the US last month and is waiting for a verdict from the FDA on the drug – which combines muscarinic agonist xanomeline tartrate and muscarinic antagonist ...

another company developing a schizophrenia drug with a novel mechanism of action. Emraclidine (formerly CVL-231) is a selective muscarinic M4 receptor-positive allosteric modulator (PAM ...

Undercover officers found illegal compounds in products undercover officers bought at Haze Daze smokeshops, according to ...

Muscarinic (M) receptors involved in the airway ... and therefore, anticholinergic drugs have been considered to be of potential interest in the treatment of asthma. The aim of this review is ...

Drug screening is the process by which potential drugs are identified and optimized before selection of a candidate drug to progress to clinical trials. It can involve screening large libraries of ...

A drug bust quickly led to high-speed chase and pursuit through the woods in the Hazleton area. On Tuesday, the Hazleton City Narcotics Unit received a tip from the Drug Enforcement Agency (DEA ...

Researchers say they have discovered a new class of antibiotics that could treat drug-resistant bacteria, the first to reach the market in nearly three decades. The new molecule, called ...

SUTNY Sumitomo Mitsui Trust Group, Inc.

The study was performed to comply with a regulatory request from the Food and Drug Administration. The specific purpose was to examine the dose proportionality of the three suppository dosage ...

Because chemogenetic control relies on DREADD expression levels, understanding and quantifying the temporal dynamics of their expression is crucial for planning long-term experiments in monkeys. In ...

If you live with allergic asthma, you can take steps to avoid your triggers and reduce your risk of an asthma attack. People living with asthma usually experience a similar set of symptoms ...

A senior detective has called on the public to help fight the "illicit drugs trade" following the murder of a gang "runner" Det Insp Justine Jenkins said "too often" the trade was "fuelling violence ...