Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

(A) The basic organization of a sarcomere subregion, showing the centralized location of myosin (A band). Actin and the z discs are shown in red. (B) A conceptual diagram representing the ...

Cancer Cachexia is a muscle and fat wasting syndrome associated with cancers of the pancreas, lung, colon. Nemaline myopathy is associated with defects in sarcomere structure and function. We are ...