Myeloma proteins were characterized for heavy-chain and light-chain antigenic determinants by immune diffusion 8 and immunoelectrophoresis 9 with monospecifie antiserums. Patients receiving ...

The ability to eliminate specific pathologic cells is creating more options for multiple myeloma patients ... which is what makes the protein such a promising target, according to Shari Kaiser ...

They show how changes in genetic material affect the protein profile of the tumor cells, and thus the mechanisms involved in the disease. Multiple myeloma is a form of cancer in which the immune ...

Multiple myeloma can lower the numbers of these cells. Blood chemistry tests check levels of proteins and other substances in your blood. Multiple myeloma can cause high calcium levels and low ...

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Response of myeloma to treatment was defined as ≥ 50% decrease of myeloma protein in the serum and ≥ 90% reduction of Bence-Jones proteinuria. Differences among various groups were compared ...

In the first study ... July 22, 2024 — The researchers report the ability of protein 'signatures' to predict the onset of 67 diseases including multiple myeloma, non-Hodgkin lymphoma ...

Darzalex and Revlimid maintenance resulted in superior outcomes versus Revlimid alone following autologous stem cell ...

We do not know what causes MGUS. There may be a link to autoimmune diseases, genetics, or environmental factors. Like multiple myeloma, MGUS starts in a type of white blood cell called plasma cells.

Previous studies revealed a positive correlation between O-GlcNAcylation and tumor growth via the stabilization of target proteins, with O-GlcNAcylation transferase (OGT) being the only enzyme capable ...