为了打破这一困境，苏州大学的研究人员勇敢地踏上探索之旅，开展了一项意义重大的研究。他们聚焦于线粒体靶向的 NOX 抑制剂米托阿朴啡林，深入探究其在海人酸（KA）诱导的兴奋性毒性中的神经保护作用及机制。最终，他们的努力取得了令人瞩目的成果 ...

Department of Drug Chemistry and Technologies, Sapienza University of Rome, P.le Aldo Moro 5, Rome 00185, Italy ...

The NADPH oxidase family (NOXs) are multisubunit transmembrane enzyme complexes involved in the generation of redox signals. Studies have shown that NOXs are highly expressed in the heart and are ...

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Key Laboratory for Forest Resource Conservation and Utilization in the Southwest Mountains of China (Ministry of Education), College of Forestry, Southwest Forestry University, Kunming, China ...

昆虫肠道免疫中，经口摄入病原体可激活两种诱导性免疫反应：免疫缺陷（Imd）途径产生抗菌肽（AMPs），以及烟酰胺腺嘌呤二核苷酸磷酸（NADPH）氧化酶产生活性氧（ROS）。其中，Duox 和 Nox 是 NADPH 氧化酶的重要成员，Duox 产生的 ROS 被认为具有杀菌作用 ...

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Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic liver disease globally and is currently estimated to affect up to 38% of the global adult population. NAFLD is a ...