Typhimurium effector SopF inactivates caspase-8 through the PDK1-RSK signaling, thereby inhibiting apoptosis and pyroptosis of IEC with the promotion of necroptosis. Consequently, SopF attenuates ...

Background: Acute lung injury (ALI) is a severe condition characterized by inflammation, tissue damage, and persistent activation of the cyclic GMP-AMP (cGAS)-stimulator of interferon genes (STING) ...

A New Ventilator-on-a-Chip Model to Study Lung Damage Sep. 19, 2024 — Scientists are now able to directly compare the different kinds of injury that mechanical ventilation causes to cells in the ...

Objective: Microglia, the central nervous system's immune cells, are crucial in neuroinflammation after ischemic brain injury. Previous single-cell and spatial transcriptomics ... and LILRB4 knockdown ...

decrease of protein NUFIP1 is found to impair DNA damage response and induce necroptosis in the intestine, thereby contributing to intestinal inflammation in male mice with inflammatory bowel disease.

Just three games after returning from an earlier injury, Kaprizov will miss at least four weeks after undergoing surgery to repair a lower-body injury he suffered against the Chicago Blackhawks on ...

An injury to the groin from falling on an object that is being straddled. Examples are playground equipment, crossbars of a bike, or a fence. Girls usually get a bruise or small cut of the outer labia ...

Neural Mechanisms of Sleep-Dependent Motor Learning Revealed in New Study on Brain Injury Rehabilitation Nov. 18, 2024 — Scientists reveal how sleep, especially naps, boosts motor learning after ...

The NFL analyzes and shares injury data as a part of ongoing efforts to advance the health and safety of players. The injury data are compiled and analyzed by IQVIA, an independent, third-party ...

Chemotherapy for lung cancer is used for different purposes depending on the type and stage of cancer you have. This includes achieving cancer remission, shrinking a tumor before surgery, killing ...