We developed morphologically realistic, multi-compartment models mouse alpha-motor neurons using the NEURON simulation environment. Simulations were conducted with and without applied extracellular ...

Abstract: Substantial physiological evidence indicates that neuron thresholds and synaptic weights in living creatures are adjusted by mechanisms quite different from those that have ordinarily been ...

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In this article, a novel synchronous image-label diffusion probability model (SDPM) is proposed for stroke lesion segmentation on NCCT using a dual-Markov diffusion process with shared noise. The ...

This important contribution to the field demonstrates the role of a single transcription factor with cell-autonomous functions in the differentiation of two distinct neuronal populations in regulating ...

How AI works through data, models, and learning. Discover how small and large AI systems process input and make intelligent ...

Unprecedented dataset links neuronal activity to synaptic wiring at the millimeter scale, offering open-access tools for ...

The interaction of AKAP11 to LC3/GABARAP on the autophagosome is proposed to regulate association of AKAP11-bound PKA with upstream regulators, including the Ser83-phosphorylating kinase on RIα ...

Apr. 10, 2025 — Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating ...