We sought to determine whether neutrophil trafficking to breast tumors is determined directly by the malignant potential of cancer cells. We found that tumor conditioned media (TCM) harvested from ...

Objective Innate immunity plays important roles in pancreatic ductal adenocarcinoma (PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune system. Here, we aimed to ...

yet another layer of heterogeneity exists among different cells due to clonal evolution or variable status of differentiation. These different levels of heterogeneity represent a major obstacle ...

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...

which is expressed on many inflammatory cell types including mast cells, eosinophils, neutrophils, innate lymphoid cells and epithelial cells and CPA3 (carboxypeptidase A3), a gene selectively ...

Cell biology is the discipline of biological sciences that studies the structure, physiology, growth, reproduction and death of cells. Research in cell biology uses microscopic and molecular tools ...

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Tissue infiltration by IgG4 plasma cells was assessed in nine patients with CSS ... Detailed histological and immunohistochemical methods are reported in the supplementary text (available online only) ...