这篇综述聚焦葡萄膜炎中 Th17 细胞，探讨其在炎症和免疫调节中的双重作用及治疗策略。 ### 引言 在免疫介导的疾病领域，Th17 细胞作为白细胞介素 - 17（IL-17）产生的 CD4 + T 辅助细胞，因其独特的功能和复杂的调控机制备受关注。它由具有不同调节方式和功能的 ...

Although the Food and Drug Administration (FDA) located H5N1 bird flu virus in samples of raw, or unpasteurized, milk in tests in four states in April 2024, and bird flu has been detected in ...

This colonization resistance displayed by female mice was mediated by an increase in IL-17A+ CD4+ T cells (Th17) and dependent on neutrophils. Ovariectomy of female mice increased MRSA burden, but ...

Chemotaxis is the directional movement of cells in response to a chemical stimulus gradient. Human pathogenic-like Th17 cells express the chemokine receptor CCR6, but how CCR6, together with other ...

Objective We aimed to investigate the role of GPR171 in modulating CD4 + T cell effector functions in IBD and evaluate its therapeutic potential. Conclusions GPR171 deficiency promotes Th17 cell ...

The complement system is one of the immune system’s oldest defense mechanisms and is historically regarded as a liver-derived and serum-active innate immune system that ‘complements’ cell-mediated and ...

这表明 GPX3 + TAAs 细胞在促进脑转移瘤的形成和转移中起着关键作用56。 GPX3 + TAAs 促进 Th17 细胞分化：通过 GO 和 KEGG 富集分析，发现 GPX3 + TAAs 的细胞特征基因在 IL-17 信号通路、Th17 细胞分化等信号通路中富集。研究人员检测了不同小鼠脑部的免疫细胞亚群 ...

Interleukin-27 (IL-27) is a member of the IL-12 family. The gene encoding IL-27 is located at chromosome 16p11. IL-27 is considered as a heterodimeric cytokine, which consists of Epstein–Barr virus ...

Chronic hepatitis B (CHB) remains a major global health challenge, with functional cure achieved in only a small subset of patients. Current oral antiviral agents effectively suppress viral ...

“Seed gave me everything I was looking for in a probiotic. They’re effective and easy to take. My gut calmed down and my frequent bloating essentially disappeared. I find traveling often makes ...