Notch can function as an oncogene ... also be inhibited by direct interaction with the glycogen-synthase-kinase-3-binding protein (GBP). As a consequence, β-Cat is not phosphorylated, avoids ...

The sixth installment of francise brings together decades of Karate Kid history by uniting iconic characters with a new ...

NOTCH signaling plays a crucial role in tumorigenesis and therapeutic resistance, with its activation linked to drug resistance in various cancers. The NOTCH family includes four receptors (NOTCH1 ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

The changes will impact roads one region of the UK, with new speed limits having come into force from Monday, March 31. Drivers have been warned to be aware of the new limits ...

The crunchy exterior and delightfully tangy flavor of fried green tomatoes is enjoyable for everyone, and one swap can make ...

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Just as President Trump is facing multiple cases in court aimed at curtailing his presidential powers, Rep. Darrell Issa ...