Nrf2敲低VSMCs通过增加炎症、促进VSMC表型转换和提高MMP水平来阻断CTS的治疗效果，表明Nrf2是AAA治疗的关键治疗靶点。Western blot分析进一步证明，Nrf2敲低大大削弱了Nrf2通路的激活以及NLRP3和焦亡通路的抑制。综上所述，这些数据表明CTS有希望通过激活Nrf2介导的抗炎 ...

Western blot results further confirmed that the upregulation of GPX4 ... First, as stated in the previous paragraph, the pathway from AMPK to Nrf2 is complex, and we have targeted only one part of ...

The paper by Gao et al. describes the effect of capsaicin on the NRF2/KEAP1 pathway. The authors carried out a set of in vitro and in vivo experiments that addressed the mechanisms of the protective ...

Conclusion: Our findings suggest that AVI is a promising therapeutic agent for OA. It exerted its protective effect by regulating the Nrf2/GPX4/HO-1 signaling axis to inhibit cartilage cell ...

West Bengal has the following Regional Transport Offices. Choose any of the following cities to get all the necessary details of the respective Regional Transport Offices. You can get details such ...

Police said there was a sudden spike in cybercrime cases in some districts in the western part of the state and along the Jharkhand border over the past month Kolkata: At least 46 suspected cyber ...

Adding to this report, a new rumor has surfaced online claiming that Rocksteady Studios and WB Games are planning a new trilogy that will adapt Batman Beyond specifically. The rumor also suggests ...

Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, China Department of Molecular, ...