Three recent manuscripts have reexamined the location of H1 within the nucleosome particle and its function in the regulation of transcription. As its name suggests, the fifth histone is ...

DNA containing a repeated nucleosome-positioning sequence was combined ... It will be essential to establish cell-free systems for chromosomal transactions such as transcriptional activation ...

The cell's genetic material, DNA, is packaged into tightly wound structures called nucleosomes. The DNA (red) is wound around two sets of core histone proteins (green) to form a kind of bead on a ...

One chromatin remodeling mechanism called "nucleosome sliding" allows a nucleosome ... information inside the nucleus of the eukaryotic cell. Chromatin remodelers help the cell access and ...

The tool, called DEFND-seq (DNA and Expression Following Nucleosome Depletion sequencing), uses an existing microfluidics platform that can process cells in parallel, allowing cancer researchers ...