A spatially and temporally resolved understanding of chromatin organization is currently one of the central topics in molecular and cell biology. Here, we used classical MD simulations and enhanced ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Single-cell DNA methylation sequencing technology has brought new perspectives to investigate epigenetic heterogeneity, supporting a need for computational methods to cluster cells based on ...

Department of Chemistry, King’s College London, Britannia House, 7 Trinity Street, London SE1 1DB, U.K.

Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...

An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

However, what types of heterogenous cancer cells in primary tumour and how they metastasise to the target organs remain largely undiscovered. Design We performed single-cell RNA sequencing and spatial ...

Look closely at this image, stripped of its caption, and join the moderated conversation about what you and other students see. By The Learning Network Look closely at this image, stripped of ...

This had never happened before. There is a remarkable story behind these cells; it's more than half a century old, but still relevant and current. Dr Maninder Ahluwalia, senior lecturer in ...