Scientists at St. Jude Children’s Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to chromatin remodeling, a process implicated in cancer and developmental ...

The basic repeating structural (and functional) unit of chromatin is the nucleosome ... It is therefore important for cells to have means of opening up chromatin fibers and/or removing histones ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

The cell's genetic material, DNA, is packaged into tightly wound structures called nucleosomes. The DNA (red) is wound around two sets of core histone proteins (green) to form a kind of bead on a ...

DNA containing a repeated nucleosome-positioning sequence was combined ... It will be essential to establish cell-free systems for chromosomal transactions such as transcriptional activation ...

A study by scientists at the Herbert Irving Comprehensive Cancer Center (HICCC) introduces a more cost-effective, scalable ...

One chromatin remodeling mechanism called "nucleosome sliding" allows a nucleosome ... information inside the nucleus of the eukaryotic cell. Chromatin remodelers help the cell access and ...

The chip that is inserted into the 10X Genomics software, allowing researchers to analyze DNA and RNA simultaneously.

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