How alterations in cell metabolism translate into specific developmental gene programs remains a major question. This study ...

we explored the regulatory role of chromatin remodeler in epigenetic mechanisms associated with short-term chromatin regulation and behavioral plasticity in locusts. First, we investigated the ...

EDINBURGH, Scotland, April 14, 2025 /PRNewswire/ -- Chromatin Bioscience, a leader in the design of synthetic promoters and gene control systems, is pleased to announce a collaboration agreement with ...

A particularly surprising discovery was that chromatin accessibility and gene expression can be independently regulated during early embryonic development. Until now, it was often assumed that open ...

EDINBURGH, Scotland, April 14, 2025 /PRNewswire/ -- Chromatin Bioscience, a leader in the design of synthetic promoters and gene control systems, is pleased to announce a collaboration agreement ...

Genome wide association studies (GWAS) have identified hundreds of genome regions containing thousands of genetic variants associated with asthma, but it's still not clear which variants have an ...

A new study combines genetic data and improved computational tools to look more closely at GWAS results for both adult-onset and childhood-onset asthma. The research identified many genetic variants ...

3). Activity screening for these SNP harbouring enhancer elements was performed as in the marker gene assessment with ATAC-seq for open chromatin and ChIP-seq of H3K4me1 and H3K27ac signals. Contact ...

When a region is involved in regulating gene expression, the chromatin "opens" to become more accessible. The amount of open ...