This modification results in a loosening of the coil. Histone modification can open chromatin, thus permitting selective binding of transcription factors that, in turn, recruit RNA polymerase II ...

For instance, histone acetylation reduces the positive charge of the histone proteins, thereby reducing their affinity for DNA and causing the chromatin to open (Figure 2). This in turn permits ...

This interaction facilitated the expression of cell elongation-related genes in open chromatin states. Then, REF6 synergizes with the phyB-PIF4 module to finely regulate hypocotyl growth under ...

"This has been a long-standing open question in biology ... developed at Northwestern to individually label and observe chromatin fibers: the bundle of DNA and proteins that form chromosomes ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how ...