Excessive osteocyte death is found in various bone diseases, such as postmenopausal osteoporosis (PMOP), and osteoclasts are found increased and activated at osteocyte death sites. Currently, apart ...

It's no coincidence that our bodies feel a little creakier as we age. The trillions of cells that make up our skeleton age ...

Scientists and researchers around the globe are investigating a series of mysteries about what happens to our bones over time.

AGEs, such as carboxymethyl lysine (CML), impair osteocyte function by activating the receptor for advanced glycation end products (RAGE), triggering oxidative stress and inflammatory responses. This ...

AGEs, such as carboxymethyl lysine (CML), impair osteocyte function by activating the receptor for advanced glycation end products (RAGE), triggering oxidative stress and inflammatory responses. This ...

Studies report an increase in osteoporosis of 8% to 11% in transgender women compared to their cisgender male counterparts before initiating hormone replacement therapy (HRT). 1 Over the past 25 years ...

Bone morphogenetic protein 2 (BMP-2) can induce the differentiation of mesenchymal stem cells (MSCs) into different osteocyte cells, including chondrocytes, adipocytes, and endothelial cells.

Cornell research could rebrand bone as an extension of the nervous system and reshape the understanding of its cellular ...

Background: Weightless bone loss is a common pathological phenomenon in weightless environments, yet its specific molecular mechanism remain incompletely elucidated. The aim of this study was to ...

Osteoporosis is a metabolic bone disorder characterized by progressive decline of bone mass and bone quality, leading to bone fragility and an increased risk of fracture. Osteoporosis occurs when ...

A federally funded research team led by Sheri Holmen, PhD, investigator at Huntsman Cancer Institute and professor in the Department of Surgery at the University of Utah (the U), is testing a new ...