In this work, the authors determine the conformational ensemble of human P-glycoprotein during active ... use mRNA display to discover peptide inhibitors of BamA, an essential factor that ...

INR: International normalized ratio; P-gp: P-glycoprotein; SSRI: Selective serotonin inhibitor. Adapted with permission from [9,21]. Events Rivaroxaban (number per 100 patient years) Warfarin ...

Debiopharm announces oral and poster presentations on data from their potential first-in-class compound Debio 1562M, a ...

Debiopharm to Reveal Insights From Their ADC, DDR Inhibitor, and Antibody Conjugation ... targeting the cell surface glycoprotein CD37 soon to undergo first-in-human evaluation.

More than 5% of the global population suffers from disabling hearing loss, primarily sensorineural hearing loss (SNHL). SNHL is often caused by factors such as vascular disorders, viral infections, ...

Clinical question: Is there an association between baseline dietary sodium intake and clinical outcomes in heart failure? Background: Dietary sodium restriction is common advice for patients with ...

Obesity and Metabolism Laboratory, The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel Laboratory of Nano Delivery ...

18/394,555 titled "Replication-Deficient Modified Vaccinia Ankara (MVA) Expressing Marburg Virus Glycoprotein (GP) and Matrix Protein (VP40)." The allowed claims generally cover prevention of ...

This manuscript focuses on understanding if and how the glycosylation of SARS-CoV2 spike protein affects a putative allosteric network of interactions controlled by the binding of a fatty acid. The ...

DelveInsight’s, “Metastatic Colorectal Cancer Pipeline Insight 2025” report provides comprehensive insights about 150+ ...