p62 and LC3 serve as autophagy inhibition controls, while p27 is used as control for CRL- and UPS-dependent degradation ... See additional biological replicates in Figure supplement 4D-E. Finally, ...

Thus, an emerging strategy for the treatment of those conditions is to inhibit cellular proliferation by targeting cell cycle regulation. Here we will review the current understanding of the ...

Mar. 26, 2025 — Researchers have developed 'tomoseqr' -- a new software tool that enables easy estimation of the three-dimensional (3D) spatial distribution of gene expression. Tomoseqr is free ...

Cell biology is the discipline of biological sciences that studies the structure, physiology, growth, reproduction and death of cells. Research in cell biology uses microscopic and molecular tools ...

MANILA, Philippines — The Philippine International Exhibition Center (PIEC), a P27-billion flagship MICE (meetings, incentives, conferences and exhibitions) infrastructure project of the Marcos ...

Understanding the differences in the mutations that ... FLIpping the Switch: Boosting Stem Cell Numbers for Therapies Mar. 10, 2025 — A single molecular switch is essential for blood stem cells ...

Figure 1: Confocal imaging of LLC-PK-1 cells in mitosis. To generate the GFP fusion protein, insert the corresponding cDNA into the multiple cloning site of a pEGFP or other appropriate ...