By analyzing huge amounts of biological data, the use of machine learning accelerates the identification of critical control ...

New research uncovers new insights into preventing chronic inflammation caused by aging-related zombie-like cells. In humans ...

Network pharmacology methods revealed that the potential targets of melatonin in AMD are closely related to ferroptosis, and indicated that the predominant pathways are significantly associated with ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The DREAM repressor complex regulates genes ...

The pre-IND meeting provided an opportunity for the Company to discuss its Investigational New Drug (IND) development plan and receive FDA guidance on nonclinical and clinical study requirements for ...

p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells - ...

signalling through the Ras–MAPK and PI3K–AKT–mTOR pathways, Wnt signalling and sonic hedgehog (SHH) signalling, along with the cell cycle-regulating RB and p53 pathways. Expression analysis ...

Pleco Therapeutics, a clinical-stage biopharmaceutical company developing novel therapies for difficult-to-treat cancers, announces a positive ...

The data to be presented encompasses five of the company’s novel drug candidates: BCR-ABL tyrosine kinase inhibitor olverembatinib (HQP1351), Bcl-2 inhibitor lisaftoclax (APG-2575), FAK/ALK/ROS1 ...

A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery and Interventional Science at University College London has systematically ...

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and ...