Edited by Ana Maria Cuervo, Albert Einstein College of Medicine, Bronx, NY; received June 7, 2024; accepted February 26, 2025 ...

Abnormal autophagy is a key factor in the development of AS ... China); NF-κΒ activator 1 was purchased from MedChemExpress (Shanghai, China); Antibodies against Beclin1, LC3B, P62, CD31, VEGF, TNF-α, ...

These experiments identify the PKA holoenzyme, primarily composed of the RIα and Cα subunits and AKAP11, as a kinase complex prominently associated with autophagy. In agreement with previous reports, ...

The occurrence of autophagy was observed by ... p-mTOR (Ser2448), p62, ATG5, Beclin1, RAPTOR, p-RAPTOR (Ser792) were purchased from Cell Signaling Technology. PKA, TSC2, and Rheb antibodies were ...

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Department of Ophthalmology, Tongji Hospital Affiliated with Tongji University, Shanghai 200065, People’s Republic of China ...

State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu 611137, China School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China Key Laboratory of ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. The authors have ...

Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, Laboratory of Neuro-system and Multimorbidity, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China ...