PCR inhibitors, primer-dimer formation, and human errors. Sample quality refers to the quantity and quality of the DNA extracted from the source material and its suitability for PCR. PCR ...

The advent of digital droplet PCR (ddPCR) has marked a paradigm shift in molecular diagnostics, offering unparalleled sensitivity, precision, and reproducibility. Within the domain of forensic science ...

Discover magnetic bead technology for efficient and reliable viral nucleic acid isolation in clinical applications.

Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ-PKAc fusion oncoprotein. However, the underlying mechanism of DNAJ-PKAc’s ...

Acurx Pharmaceuticals is a late-stage biopharmaceutical company focused on developing a new class of small molecule antibiotics for difficult-to-treat bacterial infections. The Company's approach ...

Digital PCR was therefore more sensitive and more ... With targeted therapy using tyrosine kinase inhibitors (TKIs), patients with CML may achieve deep molecular responses. Patients who reach ...

Led by Friends, collaborators included Biodesix alongside organizations from industry, government, academia, and advocacy ...

编者按：2025年美国临床肿瘤学会年会（ASCO）将于美国东部时间（GMT-5）5月30日至6月3日在芝加哥召开。本次会议聚焦肿瘤治疗前沿，将呈现化疗、内分泌治疗、免疫治疗、靶向治疗及精准医学的最新进展。日前，官网已经公布各项研究摘要题目，本文特将乳 ...

Third, DNA extraction from processed food products often represents a compromise between obtaining a high yield of DNA and keeping PCR inhibitors at low concentrations. Under such conditions ...

PCR was developed in 1983 ... “We wanted to study inhibitors of RNA polymerase, many of which are antibacterial drugs currently on the market,” says Marras. “We designed molecular beacons ...

The GoScript™ RT Mix for 1-Step RT-qPCR (50X) combines optimized quantities of GoScript™ Reverse Transcriptase, RNasin ® Plus RNase Inhibitor ... Promega's PCR Systems, enzymes and reagents ...