Recently, the research team led by Professor Zhang Zhongtao and Professor Yao Hongwei from the General Surgery Center at ...

From April 25 to 30, 2025, the American Association for Cancer Research (AACR) Annual Meeting will take place in Chicago. CStone will showcase its latest preclinical studies on five internally ...

Merck & Co.’s cancer immunotherapy Keytruda is one of the pharmaceutical industry’s biggest successes. The drug's arrival in 2014 introduced a new way of treating cancer and, over time, it became ...

Phase III DIPPER trial shows that adjuvant camrelizumab administered after induction-concurrent chemoradiotherapy ...

为解决难治性卵巢癌免疫治疗效果不佳的问题，研究人员探究菊苣酸（CA）联合 PD-1/PD-L1 阻断剂的疗效，发现联合治疗或可有效治疗卵巢癌。 研究人员采用了多种关键技术方法。首先构建了患者来源的异种移植（PDX）模型，用化疗耐药的晚期 HGSC 患者的恶性腹水和外周血单个核细胞（PBMC）注入免疫缺陷的 NSG 小鼠，成功建立了免疫活性的 PBMC-PDX 模型。接着运用单细胞 RNA ...

There has been a lot of talk about drugs targeting both PD-1 and VEGF stealing the crown held by MSD's Keytruda in cancer immunotherapy. Now, the company has made a move to try to make sure it isn ...

Haven Police Department is standing behind its officers, but also signaling potential changes, after an incident involving a child as officers worked to detain two adults.Videos show officers ordering ...

▎药明康德内容团队编辑（来源：复旦大学）近日，复旦大学附属华山医院刘杰教授、骆菲菲研究员团队在《肿瘤细胞》（Cancer Cell）发表题为“Targeting tumor monocyte-intrinsic PD-L1 by rewiring ...

帕金森病（Parkinson’s disease，PD）是一种常见的神经系统退行性疾病，除了典型的运动症状外，睡眠障碍也是困扰患者的一大难题。许多 PD 患者常常在夜晚辗转反侧，难以获得良好的睡眠质量，这不仅影响了他们的生活质量，还可能加重病情。目前，虽然知道神经递质和神经类固醇参与睡眠调节，但关于早期 PD ...

在肿瘤免疫治疗领域，淋巴细胞激活基因3（LAG3）作为继PD-1、CTLA-4后的第三大免疫检查点，其功能调控机制长期悬而未决。传统研究受限于缺乏直接信号读数和配体功能的争议，无法阐明LAG3如何通过配体结合触发抑制性功能。