A study shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States Food and Drug ...

No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

List of antibodies is given in Table S2. DAPI (Thermo Scientific) was used as a nuclear counterstain at 2.5 µg/mL final concentration. In the case of single molecule RNA in situ hybridization, slides ...

This Perspective article examines the interplay between antibody diversification mechanisms and highlights the importance of constant regions in influencing the specificity and functionality of ...

Platelet-Derived Growth Factor Receptor Alpha (PDGFRA) plays a role at multiple levels in the development of high-grade gliomas and represents a promising therapeutic target. Previous attempts to ...

脑肿瘤仍然是儿童癌症死亡的最常见原因。特别是小儿高级胶质瘤（pHGG）是一种主要致命的疾病组，诊断后的中位生存时间不 ...

Platelet-Derived Growth Factor Receptor Alpha (PDGFRA) plays a role at multiple levels in the development of high-grade gliomas and represents a promising therapeutic target. Previous attempts to ...

Platelet-Derived Growth Factor Receptor Alpha (PDGFRA) plays a role at multiple levels in the development of high-grade gliomas and represents a promising therapeutic target. Previous attempts to ...

在一项新的研究中，来自密歇根大学、丹娜法伯癌症研究院和维也纳医科大学的研究人员发现PDGFRA基因发生DNA改变的高分级胶质瘤肿瘤细胞对药物阿 ...

SUZHOU, China, March 27, 2025 /PRNewswire/ -- CStone Pharmaceuticals ("CStone", HKEX: 2616), a biopharmaceutical company dedicated to developing innovative cancer therapies, today reported 2024 annual ...