One hemisphere was frozen at –70°C and the other half was immersion-fixed in 4% PFA for 3 days at 4°C. The following secondary antibodies and reagents for immunoperoxidase labeling were purchased from ...

The goals of this report are to present the global data accrued for bedinvetmab, the first monoclonal antibody for canine osteoarthritis, and to explore reporting patterns globally and across major ...

SAN FRANCISCO--(BUSINESS WIRE)--Synthetic Design Lab, a next-generation antibody-drug conjugate (ADC) company advancing its novel SYNTHBODY therapeutic platform against a range of cancer ...

Molecular parameters governing antibody FcγR signaling and effector functions in the context of HIV envelope. Cell Reports , 2025; 44 (4): 115331 DOI: 10.1016/j.celrep.2025.115331 Cite This Page : ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Prior to the site-specific biotinylation of the rat anti-HRP ...

Several genetic variants in APP, PSEN1, and PSEN2 fit the bill, but not all. A study led by Jorge Llibre-Guerra of Washington University in St. Louis, published February 4 in Brain, explains how the ...

The French pharma is handing over $125 million upfront, with a near-term payment of $50 million to follow, for the exclusive worldwide rights to a pair of bispecific antibodies. HXN-1002 targets ...

Introduction: Antibody maturation in the lymphoid follicle produces antibodies with improved binding affinity. This process requires iterative rounds of mutation and B cell expansion, supported by T ...

BigHat Biosciences, a Californian biotech with a machine learning (ML)-guided antibody discovery and development platform, has announced a strategic collaboration with US pharma major Eli Lilly (NYSE: ...

In 2019, researchers introduced the world to a woman born in rural Angostura, Colombia, who, like so many of her relatives, carried the PSEN1 mutation. But unlike them, she did not develop ...

This class of treatment — monoclonal antibodies, special artificial proteins that carry instructions to the body’s immune system — have the potential to be a genuine all-in-one allergy ...

With this approval, this Columvi combination is the first bispecific antibody regimen available for people with DLBCL in Europe whose cancer has returned or for those who did not respond to initial ...