This month's cover highlights the article Natural variations of adolescent neurogenesis and anxiety predict the hierarchical status of adult inbred mice by Nicolas Toni, Thomas Larrieu and colleagues.

The lysosomal peptidase lysosome family plays an important role in the immune escape process of glioma, which mainly includes aspartic acid cathepsin, serine cathepsin, asparagine endopeptidases, and ...

阿尔茨海默病（Alzheimer’s disease，AD）作为一种常见的神经退行性疾病，严重影响着人们的健康和生活质量。随着全球老龄化进程的加速，AD 的发病率逐年上升，给社会和家庭带来了沉重的负担。目前，虽然对 AD 的研究已经取得了一些进展，但对于其发病机制仍未完全明确。在 AD 的众多发病因素中，衰老被认为是最主要的风险因素。然而，神经元蛋白稳态（proteostasis）下降与 AD ...

National Engineering Research Center of Ophthalmology and Optometry, School of Biomedical Engineering, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China ...

Copper (Cu) is essential for brain development and function, yet its overload induces neuronal damage and contributes to neurodegeneration and other neurological disorders. Multiple studies ...

These pages give an overview of what genes are and how they are involved in the different diseases that cause dementia. You will also find information about genetic testing for dementia. Genes ...

aMedical Clinic 1, Department of Gastroenterology, Ludwig Demling Endoscopy Center of Excellence, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany ...

Suppressing KCTD20 in both the organoids and mice prevented glutamate from triggering tau accumulation and neurodegeneration. Further experiments showed that blocking this gene’s activity activated ...