Both compounds can be distinguished from typical D 2 agonists, however, because they do not cause behavioral signs associated with activation of either normosensitive or supersensitive ...

ABSTRACT: Background: Aripiprazole is a second-generation antipsychotic known for its partial dopamine D2 agonist properties, which help reduce the risk of extrapyramidal symptoms. While effective and ...

The dopamine D2/D3 receptor partial agonist has proved to be one of the star assets to emerge from AbbVie's $63 billion mega-merger with Allergan which closed in 2020.

Muscles are attached to bones by tendons. Muscles contract to move our bones by pulling on them. However, muscles can only pull; they cannot push. This is why they usually work a joint in pairs.

AbbVie has reported new phase 3 data for its schizophrenia and bipolar disorder therapy Vraylar in treatment-resistant depression, as it waits for a decision by the FDA on the new indication.

Primary endpoint met in the 8-week treatment study (highly statistically significant). Co-administered group had a 4.4% reduction in weight compared to 1.6% for the placebo group (p<0.0001).

The partial solar eclipse on March 29, 2025, will be seen from North America, Europe, Russia and parts of Africa. Although it won't be as spectacular as North America's April 2024 total solar ...

A group that has been fighting to improve access to opioid agonist therapy for decades has filed a complaint with the BC Human Rights Tribunal. The BC Association of People on Opioid Maintenance ...

A diet low in fat and fiber, taken in small, frequent meals, has been advocated, although different diets have not been rigorously compared in patients with gastroparesis. Nutrient liquids might ...

Partial view of the solar annular eclipse in Buenos Aires, Argentina, taken on Oct. 2, 2024. Partial view of the solar annular eclipse in Buenos Aires, Argentina, taken on Oct. 2, 2024.Luis Robayo ...