Cellular key players were identified by double staining with proliferation cell nuclear antigen (PCNA) as proliferation marker and the respective cell markers for vascular smooth muscle cells ...

During DNA replication, the DNA polymerases Pol δ and Pol ε utilise the ring-shaped sliding clamp PCNA to enhance their processivity. PCNA loading onto DNA is accomplished by the clamp loaders RFC and ...

G) Representative immunofluorescent localization of proliferating (PCNA marker) PASMC (ACTA2, yellow arrow ... and functional cellular assays were performed on cells isolated from the same pulmonary ...

There was strong staining for TNF α and VEGF factors in the alcohol group. And as for PCNA, the control group and the alcohol + melatonin group showed the highest percentages of positive cells. And in ...

After metaphase, centrioles in mutant cells were either completely absent, or had a fragmented appearance (Fig 5D, 5F), with aggregates of staining that did not resemble true centrioles. We conclude ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Polo-like kinase 1 (PLK1) is a conserved ...

Department of Bioengineering, Imperial College London, South Kensington, London SW72AZ, United Kingdom Diabetes and Obesity Theme, School of Cardiovascular and Metabolic Medicine and Sciences, Faculty ...

Objectives: Lung cancer is one of the most common cancers worldwide and it is the leading cause of cancer-related mortality. Despite the treatment of patients with non-small cell lung carcinoma (NSCLC ...

CL and CT conceptualized and supervised research. JH-U, JW, KB, and CL collected samples and isolated cells. KB performed cell staining and FACS. JH-U performed bulk RNA isolations. TS performed ...