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低细胞外钠浓度对肾癌细胞影响的新发现:关乎肾癌预后与治疗的 ...
细胞周期分析显示,低 [Na?] 时 G0/G1 和 S 期细胞比例有增加趋势,G2/M 期细胞数量减少。同时,pAkt/Akt 和 pERK/ERK 比值增加,cyclin D1 和 PCNA 蛋白表达也显著上升,这表明低细胞外 [Na?] 激活了与增殖和生存相关的细胞内信号通路。 细胞侵袭和迁移:在低细胞外 [Na?] ...
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Deportation order blocked
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