How would you identify the protein that serves as a connector between DNA helicase and pol-a/primase? A simple yet often effective approach is to find proteins that directly bind to both enzymes.

Some of these — including non-nucleoside inhibitors of viral DNA polymerase and helicase–primase inhibitors — show considerable promise and could soon enter human trials. New inhibitors of ...

Primase, eine an der DNA-Synthese (Replikation) beteiligte spezifische RNA-Polymerase, die die Synthese eines kurzen RNA-Abschnitts katalysiert, der komplementär zu einem der DNA-Matrizenstränge ist.