Glioblastoma (GBM), one of the most aggressive types of brain cancer, is one of the greatest challenges for medicine, both ...

而乱序的 Prion Protein (106 - 126) (Human) (Scrambled) 由于结构改变，其作用机理与正常片段不同。研究表明，它无法像正常片段那样高效地诱导蛋白质错误折叠和聚集 。一些研究推测，它可能通过与正常片段竞争结合某些分子伴侣或参与蛋白质折叠的相关因子 ...

Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a study published in Neuron, ...

Dysfunctional Family. A family tree of tau folds now incorporates two new structures—P301L, P301T (bottom)—and fills in ...