Knight says that the method of transmission that Collinge identified is “extremely unusual,” and there’s no evidence that ...
Glioblastoma (GBM), one of the most aggressive types of brain cancer, is one of the greatest challenges for medicine, both ...
为了了解朊病毒在癌症生物学中的重要性,首先需要了解GBM的作用机制。正如Lopes所解释的那样,手术和替莫唑胺治疗会杀死快速增殖并形成肿瘤“团块”的细胞。然而,所谓的肿瘤干细胞(胶质母细胞瘤干细胞)在脑组织中仍然处于休眠状态。当它们再次活跃时,它们能够再次协调肿瘤生长。
A silent but deadly epidemic is creeping through North America and scientists are sounding the alarm.
Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a newly published study, ...
also called Creutzfeldt-Jakob disease (CJD), results from the misfolding of a normal prion protein—an essential protein present in everyone. The misfolded form of the protein, the cause of CJD ...
Certain neurodegenerative disorders are characterized by the progressive accumulation of insoluble deposits of distinct misfolded proteins. In general, mutations causing inherited forms of the ...
Glioblastoma stem cells with fluorescent labeling for prion protein (red), CD44 protein (green), and cell nucleus (blue) ...
Clumps of killer rogue prion proteins form in the brain, and make holes, causing it to look like a sponge. At the time, scientists knew about a sheep disease called scrapie that damaged the brain ...