Amyotrophic lateral sclerosis (ALS) is a relatively rare but very serious disease of the nervous system. A cure is not yet ...

Amyloids can be broadly defined as insoluble protein aggregates containing a characteristic highly ordered, β-sheet-rich structural motif. The latter can be identified histologically with dyes ...

Alpha-1-antitrypsin is a so-called protease inhibitor, a type of enzyme inhibitor. It is produced in the liver but exerts its ...

Home > Press release: Neurodegenerative disease ALS: Cellular ... Researchers at Goethe University, Johannes Gutenberg University Mainz and Kiel University discover possible method for preventing ...

A central challenge in DSP is product stability, as biopharmaceutical proteins can be highly sensitive to environmental stresses, causing protein aggregation, reduced therapeutic efficacy and ...

A new AI tool called RibbonFold is revolutionizing how scientists understand misfolded proteins linked to Alzheimer’s and Parkinson’s.

A novel artificial intelligence (AI) tool has revealed how disease-linked proteins misfold into harmful structures, a key ...

In a study published in the Journal of the American Chemical Society, scientists explore how a brain protein called tau changes its behavior when a small chemical group called a phosphate attaches to ...

Parkinson's disease (PD) and Lewy body dementia (LBD) are incurable and progressive neurodegenerative disorders, with some ...

Why do problems occur with a special variant of 'protein glues', the split inteins, that severely limit their use in producing proteins? A team has now answered this question.