Amyloids can be broadly defined as insoluble protein aggregates containing a characteristic highly ordered, β-sheet-rich structural motif. The latter can be identified histologically with dyes ...

Du et al. address the cell cycle-dependent clearance of misfolded protein aggregates mediated by the endoplasmic reticulum (ER) associated Hsp70 chaperone family and ER reorganisation. The ...

Neurodegenerative diseases like Huntington’s disease pose significant challenges to modern medicine. Recent research has ...

A novel artificial intelligence (AI) tool has revealed how disease-linked proteins misfold into harmful structures, a key ...

actually at Organic Polymers Chemistry Laboratory (LCPO), CNRS-University of Bordeaux, 33600 Pessac, France Active principle ingredients (API) and protein aggregation are of the utmost importance ...

A central challenge in DSP is product stability, as biopharmaceutical proteins can be highly sensitive to environmental stresses, causing protein aggregation, reduced therapeutic efficacy and ...

A new study suggests that targeting the protein alpha-synuclein could be a possible new target for treating melanoma.

A novel artificial intelligence (AI) tool has revealed how disease-linked proteins misfold into harmful structures, a key advance in understanding neurodegenerative disorders such as Alzheimer's and ...

professor Elizabeth Bess presented on one possible molecular mechanism that might tie microbiome problems to protein aggregation and neuron death. When oxygen is unavailable, some gut bacteria can ...

Parkinson's disease (PD) and Lewy body dementia (LBD) are incurable and progressive neurodegenerative disorders, with some ...