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Navinci Diagnostics AB, Uppsala, Sweden.

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Mechanisms were explored via LC‒MS/MS, coimmunoprecipitation, laser microirradiation, immunofluorescence, the homologous recombination (HR) or non-homologous end joining (NHEJ) reporter system, in ...

The Proximity Network Assay at the core of the Pixelgen Proxiome Kit allows researchers to study protein interactomics at high scale, adds the company spokesperson.

The functional consequences of the identified GLK germline or somatic variants were investigated using site-directed mutagenesis and cell transfection, followed by reporter assays, mass spectrometry, ...

They call it the "intelligent sequential proximity ligation assay," or iseqPLA. "It's a smart test that can look at proteins and how they interact with each other in space," said Coskun ...

胰腺癌（PDAC）死亡率高，缺乏有效疗法。研究人员聚焦 TRPM7 激酶结构域，用 CRISPR-Cas9 技术研究其对胰腺癌细胞命运的影响。结果发现该结构域维持癌细胞间质表型，与 PAK1 相互作用，影响肿瘤发生和转移，或成 PDAC 治疗新靶点。