Seven-transmembrane receptors (7TMRs), also known as G protein-couple receptors, are the largest class of transmembrane receptors and a common target for therapeutics. Initially thought to signal ...

The finding that temperature influences how glutamate binds to neuronal receptor proteins to initiate signal transduction reveals the mechanics of one of the brain’s most important processes.

In this important study, Li and others identified cell membrane receptors for juvenile hormone (JH), a terpenoid hormone in insects that regulates their development and reproduction. While ...

However, comprehensive information on the expression and prognostic value of co-inhibitory molecules, including co-inhibitory receptors and their ligands, in different cancers is not yet available.

TREM2 is a crucial membrane receptor protein with immunomodulatory functions that help inhibit inflammation ... and binds to phosphatidylserine on the apoptotic cell membrane (PtdSer) to mediate ...

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TAM 受体家族的激活依赖于磷脂酰丝氨酸（PtdSer）的存在，细胞凋亡时，胞内 ATP 减少，胞质 Ca 2+ 浓度升高，激活 TAM 受体识别凋亡细胞外表面的 PtdSer，Gas6 和 Pros1 与 PtdSer 结合后，激活 TAM 受体并启动下游信号通路。 TAM 受体在肿瘤微环境中的动力学特征 在肿瘤 ...