The chimeric fusion oncogene early B-cell factor 1–platelet-derived growth factor receptor-β (EBF1-PDGFRB) is a recurrent lesion observed in Philadelphia-like B-acute lymphoblastic leukemia (B ...

Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs), especially, exosomes are considered to have diverse therapeutic effects for various significant diseases. MSC-derived exosomes (MSCex) ...

GA, UNITED STATES, March 3, 2025 /EINPresswire.com/ -- A new study has identified a critical mechanism that could lead to substantial advancements in the treatment of ...

By elucidating its interaction with RUNX1, we can now envision therapeutic strategies that target this axis across diverse AML subtypes. The discovery of JMJD1C's role in AML cell survival opens a new ...

This important study reports single-nucleus multiomics-based profiling of transcriptome and chromatin accessibility of mouse XX and XY primordial germ cells (PGCs). The main conclusions of this study, ...

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Deoxynivalenol (DON) is the most common mycotoxin that frequently contaminates human food and animal feed, resulting in intestinal diseases and systemic immunosuppression. Lithocholic acid (LCA) ...

Treatment stratification in ALL includes diverse (cyto)genetic aberrations, requiring diverse tests to yield conclusive data. We optimized the diagnostic workflow to detect all relevant aberrations ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. An evolutionarily conserved micropeptide, ...

Chronic myelomonocytic leukemia is a rare hematopoietic malignancy characterized by persistent monocytosis in peripheral blood and bone marrow dysplasia.