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ACT001:抑制 NF-κB/NLRP3 通路,对抗骨质疏松的新希望
为解决骨质疏松治疗难题,河北大学研究人员开展 ACT001 对骨质疏松作用的研究。结果发现 ACT001 可抑制 RANKL 诱导的破骨细胞分化,通过抑制 NF-κB/NLRP3 通路减轻 OVX 诱导的骨丢失,为骨质疏松治疗提供新方向。
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