Potentially best-in-class RAS-targeting franchise advancing with both ERAS-0015 and ERAS-4001 expected to enter the clinic in 2025Ongoing Phase 3 ...

Dogs that have oral squamous cell carcinomas often need surgery that disfigures their jaws and lower their quality of ...

They result from germline mutations in genes encoding kinases and other proteins interacting in the RAS-MAPK pathway. This review summarises these disorders, discussing their presenting features and ...

Cherra and Lamb discuss the dynamic interplay between the Ras and Rap small GTPase signaling pathways, historically viewed as antagonistic. Their work highlights the coordinated roles of these ...

Janus kinase/signal transduction and transcription activation (JAK/STAT) pathways were originally thought to be intracellular signaling pathways that mediate cytokine signals in mammals. Existing ...

Along an industrial stretch of roadway in New Jersey’s biggest city, Newark Mayor Ras Baraka appeared with immigrants rights ...

Investigating GLP-1 RAs reveals their impact on women's health, addressing metabolic disorders, reproductive health, and ...

Verastem (NASDAQ:VSTM – Free Report) had its price objective cut by Royal Bank of Canada from $16.00 to $14.00 in a report released on Friday morning,Benzinga reports. They currently have an ...

Black Diamond Therapeutics has found a partner for its deprioritized solid tumor candidate. Five months after cutting support ...

Farnesylated and palmitoylated Ras proteins (P, F) then enter the secretory vesicular pathway for transport to the plasma membrane (PM), where their dual lipid modifications enhance association.

Inheritance of Manasseh; Canaanites forced to pay taxes to Israelites; Tabernacle set up at Shiloh; remainder of the land divided. And the whole congregation of the children of Israel assembled ...