UF scientists have developed a compound that safely activates delta opioid receptors, offering pain relief without ...

University of Florida scientists have helped identify a novel drug compound that selectively activates pain-altering ...

What are the most concerning consequences of the drug and other weight-loss medicines? - Gastrointestinal and cardiovascular ...

If we can develop drugs that safely target the delta receptor, we might achieve effective pain relief without the lethal concerns." The need for safer pain treatments is urgent.

The intracellular loop that links the TM3 and TM4 transmembrane segment is unique to eukaryotic receptors but remains a largely unexplored territory for drug design. With the exception of an ...

People taking GLP-1 drugs can decrease fat mass while minimizing muscle loss with a few key strategies that include proper ...

The recent uptick and rise in popularity of GLP-1 drugs for addressing weight loss and obesity has led to an increase in U.S. litigation ...

Mounjaro, a new treatment for Type 2 diabetes and obesity, has been launched in India after CDSCO approval. The drug, ...

Receptor pharmacology is the study of the interactions of receptors with drugs/pharmaceuticals and other xenobiotics. A basic tenet of receptor pharmacology is that a drug’s effect is directly ...

Objective: To review drug interaction studies of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and concurrent oral medications. Data Sources: PubMed was searched (to December 5, 2011 ...

A new study shows how common gut bacteria can metabolize certain oral medications that target cellular receptors called GPCRs, potentially rendering these important drugs less effective.

A study published in Nature Chemistry by researchers from the University of Pittsburgh and Yale University shows how common ...