Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

This film creatively illustrates the process of protein synthesis through dance, symbolizing the assembly of amino acids into proteins. It explains how genes encode instructions for amino acid ...

Only recently has the ribosome - one of the oldest molecular machines in evolutionary terms - been recognized as an active regulator of gene expression at the level of protein biosynthesis.

Following the COVID-19 pandemic, mRNA-based vaccines have been shown to provide rapid and precise immune responses, however, this technology has much wider applications. Many leading pharma and ...

mRNA is the most variable class of RNA ... genes that are being expressed in a cell at a particular point in time. Ribosomes are the sites in a cell in which protein synthesis takes place.

By recruiting ribosomes, IRES sequences enable the initiation of translation independently of the 5' cap of the mRNA. This is a protective cap with which the host's own mRNA strands are equipped ...